Yuna Blum

I am a research scientist at the CIT Program (Cartes d’Identité des Tumeurs) at the French League Against Cancer.

Keywords: Genomics, biostatistics, bioinformatics

We won the first prize ! Thank you to the organizers for this amazing week, such great interactions and a wonderful location !

I presented a collaborative work with Didier Jean’s team (Functional genomics of solid tumor, Inserm Unit U1162, Hôpital Saint-Louis, Paris) about MPM heterogeneity characterization using molecular gradients. In our study, we show using a deconvolution approach, that molecular gradients bring new light on intra-tumor heterogeneity of MPM, leading to a reconsideration of existant MPM molecular classifications. We further show that this new way of thinking the pathology provides a significant contribution to clinical applications with implications in prognosis and therapeutic strategies, including immunotherapies and targeted therapies.

Scientific Paper: http://www.cell.com/cell-reports/abstract/S2211-1247(17)31606-6

In brief (french):